Article
Biological effects of active oxygen on an X-ray-sensitive mutant mouse cell line (SL3-147).
Mutation research - 1 May 1995
Murakami M, Eguchi-Kasai K, Sato K
Abstract excerpt
The biological effects of active oxygen species were examined in a mutant mouse cell line (SL3-147) that is deficient in the repair of DNA double-strand breaks. This mutant cell line shows different sensitivities to X-rays, hydrogen peroxide, paraquat and menadione when compared to the wild-type...
Topics
- Animals
- Cell Line
- Cell Survival
- DNA Damage
- DNA Repair
- Electrophoresis, Gel, Pulsed-Field
- Mice
- Mutation
- Paraquat
- Radiation Tolerance
- Reactive Oxygen Species
- Vitamin K