Article
Relationships between DNA damage and the survival of radiosensitive mutant Chinese hamster cell lines exposed to gamma-radiation: Part 2. Effect of cellular redox status.
International journal of radiation biology - 1 Feb 1993
Murray D, Prager A, Meyn R E, Davison S, Green A D
Abstract excerpt
To characterize further the nature of the defects underlying the differential radiosensitivities of the Chinese hamster ovary cell lines NM2, EM9, and UV41, we compared the abilities of anoxia and of the thiol WR-1065 to protect these mutants and their parent cell line, AA8, from the lethal effec...
Topics
- Animals
- CHO Cells
- Cell Survival
- Cesium Radioisotopes
- Cricetinae
- DNA Damage
- Dose-Response Relationship, Radiation
- Gamma Rays
- Mercaptoethylamines
- Mutation
- Oxidation-Reduction
- Oxygen
- Radiation Genetics
- Radiation Tolerance
- Radiation-Protective Agents