Article
Early induction of genetic instability and apoptosis by arsenic in cultured Chinese hamster cells.
Mutagenesis - 1 Mar 2002
Sciandrello Giulia, Barbaro Roberta, Caradonna Fabio, Barbata Giusi
Abstract excerpt
In order to assess at what time from the beginning of exposure inorganic arsenic can give rise to genetic instability and trigger apoptosis, V79-C13 Chinese hamster cells were treated with 10 microM sodium arsenite for 24 h. Under these conditions, cell survival was >70% and cells showed neither an increase in chromosome aberration frequency nor a delay in cell cycle progression. Investigations, which were...
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