Bend induced by the phage phi 29 transcriptional activator in the viral late promoter is required for activation.

doi:10.1016/0022-2836(90)90072-t

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Bend induced by the phage phi 29 transcriptional activator in the viral late promoter is required for activation.

Journal of molecular biology - 20 Feb 1990

Rojo F, Zaballos A, Salas M

Abstract excerpt

Transcription initiation from the Bacillus subtilis phage phi 29 late A3 promoter requires the viral protein p4, a transcriptional activator. Protein p4 binds to a region of the A3 promoter, located between nucleotides -50 and -100 relative to the transcription start site, that presents a sequence-directed curvature. This curvature is enhanced when protein p4 binds to the promoter. A number of deletion mutants at...

Topics

Amino Acid Sequence
Bacillus subtilis
Bacteriophages
Base Sequence
Chromosome Deletion
DNA, Viral
Deoxyribonuclease I
Genes, Viral
Models, Molecular
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Conformation

Nucleotide Mapping

Plasmids

Promoter Regions, Genetic

Protein Binding

Trans-Activators

Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 2107318
DOI: 10.1016/0022-2836(90)90072-t

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2107318-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bend induced by the phage phi 29 transcriptional activator in the viral late promoter is required for activation.PMID 2107318Read ↗

Short N-terminal deletions in the phage phi 29 transcriptional activator protein impair its DNA-binding ability.Semantic proximity Read ↗

A DNA curvature can substitute phage phi 29 regulatory protein p4 when acting as a transcriptional repressor.Semantic proximity Read ↗

A Mutation in the C-terminal domain of the RNA polymerase alpha subunit that destabilizes the open complexes formed at the phage phi 29 late A3 promoter.Semantic proximity Read ↗

Identification of a phage-coded DNA-binding protein that regulates transcription from late promoters in bacteriophage P4.Semantic proximity Read ↗

Mutational analysis of the activator of late transcription, Alt, in the lactococcal bacteriophage TP901-1.Semantic proximity Read ↗

Identification of the domains for DNA binding and transactivation function of C protein from bacteriophage Mu.Semantic proximity Read ↗

DNA sequence-specific recognition by a transcriptional regulator requires indirect readout of A-tracts.Semantic proximity Read ↗

The bacteriophage T4 late-transcription coactivator gp33 binds the flap domain of Escherichia coli RNA polymerase.Semantic proximity Read ↗

Identification of upstream sequences essential for activation of a bacteriophage P2 late promoter.Semantic proximity Read ↗

DNA unwinding mechanism for the transcriptional activation of momP1 promoter by the transactivator protein C of bacteriophage Mu.Semantic proximity Read ↗

Mutations affecting two adjacent amino acid residues in the alpha subunit of RNA polymerase block transcriptional activation by the bacteriophage P2 Ogr protein.Semantic proximity Read ↗

Mutational analysis of a C-dependent late promoter of bacteriophage Mu.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.