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Article

Regulatory elements for expression of the alkA gene in response to alkylating agents.

Molecular & general genetics : MGG - 1 Dec 1992

Furuichi M, Yu C G, Anai M, Sakumi K, Sekiguchi M

Abstract excerpt

Expression of the alkA gene in Escherichia coli is controlled by Ada protein, which binds to a specific region of the alkA promoter and enhances further binding of RNA polymerase holoenzyme to the complex. To determine the sequence recognized by the Ada protein, we introduced various base substitutions into the promoter region of alkA and examined their effects on expression of the gene, both in vivo and in...

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PMID: 1494347
DOI: 10.1007/BF00279639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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