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Article

The incidence and prognostic significance of mutations in codon 13 of the N-ras gene in acute myeloid leukemia.

Leukemia - 1 Oct 1994

Coghlan D W, Morley A A, Matthews J P, Bishop J F

Abstract excerpt

To determine the incidence and prognostic significance of mutation in the N-ras gene in de novo acute myeloid leukemia (AML) we performed an analysis of bone marrow smears from 219 patients with de novo AML treated between 1984 and 1986 and followed for at least six years. DNA extracted from bone...

Topics

Base Sequence
Chi-Square Distribution
Codon
Cohort Studies
Female
Follow-Up Studies
Genes, ras
Humans
Leukemia, Myeloid, Acute
Male
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prognosis

Proportional Hazards Models

Restriction Mapping

Sensitivity and Specificity

Survival Rate

Source

Identifiers

PMID: 7934163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7934163-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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