N-ras mutation in acute myeloid leukemia: incidence, prognostic significance and value as a marker of minimal residual disease.

doi:10.3109/00313029309068903

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Article

N-ras mutation in acute myeloid leukemia: incidence, prognostic significance and value as a marker of minimal residual disease.

Pathology - 1 Jan 1993

Casey G, Rudzki Z, Roberts M, Hutchins C, Juttner C

Abstract excerpt

The polymerase chain reaction (PCR) and allele specific oligonucleotide (ASO) hybridization have been used to investigate the incidence of N-ras mutation in acute myeloid leukemia (AML). The prognostic significance of these mutations and their value as markers of minimal residual disease have als...

Topics

Adolescent
Adult
Aged
Female
Genes, ras
Genetic Markers
Humans
Incidence
Leukemia, Myeloid, Acute
Male
Middle Aged
Mutation
Prognosis
Recurrence
Remission Induction
Retrospective Studies

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