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Article

Characterization of a set of T7 RNA polymerase active site mutants.

The Journal of biological chemistry - 7 Oct 1994

Bonner G, Lafer E M, Sousa R

Abstract excerpt

We have evaluated the elongation rates, processivities, and abortive transcription characteristics of a set of T7 RNA polymerase mutants that map to the polymerase active site. The effects of these mutations on transcription are complex: they cause decreases in activity and processivity during both the processive and abortive phases of transcription and exhibit disproportionate decreases in activity and...

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PMID: 7929200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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