Article
Functional architecture of T7 RNA polymerase transcription complexes.
Journal of molecular biology - 10 Aug 2007
Nayak Dhananjaya, Guo Qing, Sousa Rui
Abstract excerpt
Bacteriophage T7 RNA polymerase is the best-characterized member of a widespread family of single-subunit RNA polymerases. Crystal structures of T7 RNA polymerase initiation and elongation complexes have provided a wealth of detailed information on RNA polymerase interactions with the promoter and transcription bubble, but the absence of DNA downstream of the melted region of the template in the initiation...
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