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Article

Isolation and characterization of transcription fidelity mutants.

Biochimica et biophysica acta - 1 Jul 2012

Strathern Jeffrey N, Jin Ding Jun, Court Donald L, Kashlev Mikhail

Abstract excerpt

Accurate transcription is an essential step in maintaining genetic information. Error-prone transcription has been proposed to contribute to cancer, aging, adaptive mutagenesis, and mutagenic evolution of retroviruses and retrotransposons. The mechanisms controlling transcription fidelity and the biological consequences of transcription errors are poorly understood. Because of the transient nature of mRNAs and...

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Identifiers

PMID: 22366339
DOI: 10.1016/j.bbagrm.2012.02.005
PMCID: PMC7511983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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