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Article

Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder.

British journal of cancer - 1 Oct 1994

Brewster S F, Gingell J C, Browne S, Brown K W

Abstract excerpt

Somatic allelic loss is regarded as a hallmark of tumour-suppressor gene (TSG) inactivation. Thirty-one human bladder transitional cell carcinomas (TCCs) were examined for allelic loss at five chromosome 18q loci, including the DCC gene (deleted in colorectal carcinoma) and at chromosome 11p15 in...

Topics

Alleles
Carcinoma, Transitional Cell
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 18
DNA Fingerprinting
DNA, Neoplasm
Female
Gene Deletion
Genes, DCC
Genetic Variation
Heterozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Muscle, Smooth

Neoplasm Invasiveness

Polymorphism, Restriction Fragment Length

Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 7917921
DOI: 10.1038/bjc.1994.376
PMCID: PMC2033387

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7917921-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder.PMID 7917921Read ↗

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