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Article

Prognostic significance of allelic lost at chromosome 18q21 for stage II colorectal cancer.

Gastroenterology - 1 Jun 1998

Carethers J M, Hawn M T, Greenson J K, Hitchcock C L, Boland C R

Abstract excerpt

BACKGROUND & AIMS: Allelic loss of a portion of chromosome 18q and lack of expression of deleted in colorectal cancer (DCC) protein has been reported as an adverse prognostic indicator for stage II (i.e., Dukes' B2) colorectal cancer. Our aim was to assess whether the DCC gene locus was responsib...

Topics

Aged
Alleles
Chromosomes, Human, Pair 18
Colorectal Neoplasms
DNA, Neoplasm
Female
Humans
Loss of Heterozygosity
Male
Microsatellite Repeats
Middle Aged
Multivariate Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Invasiveness

Neoplasm Staging

Prognosis

Proportional Hazards Models

Survival Analysis

Source

Identifiers

PMID: 9609755
DOI: 10.1016/s0016-5085(98)70424-x

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9609755-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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