Article
Genetic alterations in bladder cancer.
Lancet (London, England) - 21 Aug 1993
Dalbagni G, Presti J, Reuter V, Fair W R, Cordon-Cardo C
Abstract excerpt
To see whether genetic alterations follow a sequence of events leading to bladder cancer progression, 60 paired bladder tumours and normal tissues were analysed with polymorphic DNA markers, correlating loss of heterozygosity (LOH) at candidate tumour suppressor gene sites with pathological indices of poor clinical outcome. Distinct genotypic patterns were associated with early and late stages of bladder cancer....
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