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Article

Genetic alterations in bladder cancer.

Lancet (London, England) - 21 Aug 1993

Dalbagni G, Presti J, Reuter V, Fair W R, Cordon-Cardo C

Abstract excerpt

To see whether genetic alterations follow a sequence of events leading to bladder cancer progression, 60 paired bladder tumours and normal tissues were analysed with polymorphic DNA markers, correlating loss of heterozygosity (LOH) at candidate tumour suppressor gene sites with pathological indices of poor clinical outcome. Distinct genotypic patterns were associated with early and late stages of bladder cancer....

Topics

Alleles
Chromosome Deletion
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 3
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 9
Genes, Tumor Suppressor
Genotype
Heterozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Invasiveness

Neoplasm Staging

Prognosis

Urinary Bladder Neoplasms

Source

Identifiers

PMID: 8102431
DOI: 10.1016/0140-6736(93)91595-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8102431-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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