Article
Cluster of allele losses within a 2.5 cM region of chromosome 10 in high-grade invasive bladder cancer.
Oncogene - 19 Feb 1998
Kagan J, Liu J, Stein J D, Wagner S S, Babkowski R, Grossman B H, Katz R L
Abstract excerpt
A limited number of previous studies have indicated a low frequency of chromosome 10 allele losses and deletions in bladder cancers. We investigated the involvement of chromosome 10 in advanced bladder cancers. Loss of heterozygosity (LOH) was analysed in 19 microsatellite loci in 20 grade III invasive transitional cell carcinomas. Nine (45%) of the 20 tumors had at least one allele loss on the long arm of...
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