Article
Study of allelic losses on 3p, 6q, and 17p in human urothelial cancer.
Cancer genetics and cytogenetics - 1 Jul 1999
Bernués M, Casadevall C, Caballín M R, Miró R, Ejarque M J, Chéchile G, Gelabert A, Egozcue J
Abstract excerpt
Forty-eight transitional cell carcinomas of the bladder and three transitional cell carcinomas of the renal pelvis were examined for loss of heterozygosity (LOH) on chromosomes 3p, 6q, and 17p. The most frequent allelic loss was seen on 17p (18/36, 50%) followed by 6q (6/22, 27%), and 3p (5/22, 23%). In cases with LOH at more than one locus, the same DNA sample often varied in degree of signal reduction for...
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