Article
Genetic alterations of microsatellites on chromosome 18 in human breast carcinoma.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Mar 1995
Huang T H, Yeh P L, Martin M B, Straub R E, Gilliam T C, Caldwell C W, Skibba J L
Abstract excerpt
Allelic alterations of chromosome 18 microsatellites were determined using normal and tumor DNA pairs from 29 patients with infiltrating ductal carcinoma of the breast. Loss of heterozygosity was detected in 62% (18 of 29 patients) of the tumors at one or more of these microsatellites. Eight of t...
Topics
- Alleles
- Base Sequence
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 18
- DNA, Neoplasm
- DNA, Satellite
- Female
- Heterozygote
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction