Article
Allelic losses of chromosomes 9, 11, and 17 in human bladder cancer.
Cancer research - 1 Jan 1990
Tsai Y C, Nichols P W, Hiti A L, Williams Z, Skinner D G, Jones P A
Abstract excerpt
Twenty-five human bladder tumors were examined for loss of heterozygosity of markers on chromosomes 6p, 9q, 11p, 14q, and 17p. These studies show that all of the markers were reduced to homozygosity in at least some of the tumors. They also confirmed earlier studies by Fearon et al. [Nature (Lond.), 318: 377-380, 1985] that approximately 40% of bladder tumors were reduced to homozygosity for markers on chromosome...
Topics
- Alleles
- Blotting, Southern
- Carcinoma, Transitional Cell
- Chromosome Deletion
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 9
- DNA Probes
- DNA, Neoplasm
- Genetic Carrier Screening
- Humans