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Article

Loss of heterozygosity on chromosomes 11 and 17 are markers of recurrence in TCC of the bladder.

British journal of cancer - 14 Dec 2001

Edwards J, Duncan P, Going J J, Grigor K M, Watters A D, Bartlett J M

Abstract excerpt

Approximately 2/3 of patients diagnosed with superficial transitional cell carcinoma of the urinary bladder (TCC) will recur within 2 years. Loss of chromosome 9 and loss of heterozygosity (LOH) at 9q34 in index TCCs identify a subset of patients at high risk of recurrence. This study explores genetic alterations on chromosomes 4, 8, 11 and 17 as predictors of recurrence. A total of 109 carcinomas were...

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Identifiers

PMID: 11747332
DOI: 10.1054/bjoc.2001.2159
PMCID: PMC2364026

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Source receipt: pubmed, retrieved 7 Sept 2026.

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