Article
A population-based study of immunohistochemical detection of p53 alteration in bladder cancer.
British journal of cancer - 19 Apr 2004
Kelsey K T, Hirao T, Schned A, Hirao S, Devi-Ashok T, Nelson H H, Andrew A, Karagas M R
Abstract excerpt
The molecular pathology of bladder cancer has been the subject of considerable interest and mutation of the p53 gene, which has been associated with more invasive bladder cancer, has been widely studied. Further, there is evidence that p53 inactivation (either mutation or protein dysregulation), independent of stage, may be predictive of bladder cancer progression. In an effort to avoid possible biases associated...
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