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Article

Genetic and immunophenotype analyses of TP53 in bladder cancer: TP53 alterations are associated with tumor progression.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 2004

Erill Nadina, Colomer Anna, Verdú Montserrat, Román Ruth, Condom Enric, Hannaoui Naim, Banús Josep M, Cordon-Cardo Carlos, Puig Xavier

Abstract excerpt

Altered p53 status is a frequent event in bladder cancer and reported to have prognostic significance. We studied the TP53 gene and its product in 76 patients affected with urinary bladder carcinomas by immunohistochemistry (mAb DO-7), polymerase chain reaction single-strand conformational polymorphism (exons 4-8) followed by direct sequencing of shifted bands, and loss of heterozygosity in 17p (p53CA). H-RAS...

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Share to Carcinoma, Transitional Cell
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to DNA, Neoplasm

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 15538112
DOI: 10.1097/01.pdm.0000137098.03878.00

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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