Article
Sensitivity and specificity of p53 protein detection by immunohistochemistry in patients with urothelial bladder carcinoma.
Urologia internationalis - 1 Jan 2007
Salinas-Sánchez Antonio S, Atienzar-Tobarra Manuel, Lorenzo-Romero Juan G, Sánchez-Sánchez Francisco, Giménez-Bachs José M, Donate-Moreno María J, Pastor-Navarro Héctor, Hernández-Millán Ibrahim, Segura-Martín Miguel, Escribano-Martínez Julio
Abstract excerpt
OBJECTIVE: To analyze the correlation between the genotypic and phenotypic patterns of p53 in patients with transitional cell carcinoma (TCC) of the urinary bladder. MATERIALS AND METHODS: Cross-sectional study of 73 patients diagnosed with TCC. DNA was obtained from the tumor tissue to perform polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) of exons 5-9 of the p53 gene, with...
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