Article
Substrate specificity of allelic variants of the TAP peptide transporter.
Immunity - 1 Dec 1994
Heemels M T, Ploegh H L
Abstract excerpt
The transporter associated with antigen processing (TAP) translocates peptides from the cytosol into the lumen of the endoplasmic reticulum (ER). An important determinant for the specificity of translocation is the identity of the C-terminal residue of the peptide substrate. In the rat, a suitabl...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Alleles
- Amino Acid Sequence
- Animals
- Binding, Competitive
- Biological Transport
- Liver
- Microsomes
- Molecular Sequence Data
- Rats
- Rats, Inbred F344
- Rats, Inbred Lew
- Sequence Analysis
- Substrate Specificity