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Article

Substrate specificity of allelic variants of the TAP peptide transporter.

Immunity - 1 Dec 1994

Heemels M T, Ploegh H L

Abstract excerpt

The transporter associated with antigen processing (TAP) translocates peptides from the cytosol into the lumen of the endoplasmic reticulum (ER). An important determinant for the specificity of translocation is the identity of the C-terminal residue of the peptide substrate. In the rat, a suitable C terminus is necessary but not always sufficient for a peptide to be selected for translocation. Here we show that...

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PMID: 7895166
DOI: 10.1016/s1074-7613(94)80019-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Substrate specificity of allelic variants of the TAP peptide transporter.PMID 7895166Read ↗

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