Article
Peptide translocation by variants of the transporter associated with antigen processing.
Science (New York, N.Y.) - 24 Dec 1993
Heemels M T, Schumacher T N, Wonigeit K, Ploegh H L
Abstract excerpt
Major histocompatibility complex (MHC) class I molecules associate with peptides that are delivered from the cytosol to the lumen of the endoplasmic reticulum by the transporter associated with antigen processing (TAP). Liver microsomes of SHR and Lewis rats, which express different alleles of TA...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Alleles
- Amino Acid Sequence
- Animals
- Antigen Presentation
- Biological Transport
- Carrier Proteins
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- In Vitro Techniques
- Microsomes, Liver
- Molecular Sequence Data
- Oligopeptides
- Rats
- Rats, Inbred BN
- Rats, Inbred Lew