Article
Transporters from H-2b, H-2d, H-2s, H-2k, and H-2g7 (NOD/Lt) haplotype translocate similar sets of peptides.
Proceedings of the National Academy of Sciences of the United States of America - 20 Dec 1994
Schumacher T N, Kantesaria D V, Serreze D V, Roopenian D C, Ploegh H L
Abstract excerpt
The TAP complex transports peptides from the cytosol into the lumen of the endoplasmic reticulum for presentation by major histocompatibility complex class I molecules. A limited degree of sequence polymorphism has been observed for the mouse TAP1 and TAP2 genes by restriction fragment length pol...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Adenosine Triphosphate
- Alleles
- Amino Acid Sequence
- Animals
- Biological Transport, Active
- Endoplasmic Reticulum
- H-2 Antigens
- Haplotypes
- Mice
- Mice, Inbred NOD