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Article

Transporter associated with antigen processing preselection of peptides binding to the MHC: a bioinformatic evaluation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2004

Doytchinova Irini, Hemsley Shelley, Flower Darren R

Abstract excerpt

TAP is responsible for the transit of peptides from the cytosol to the lumen of the endoplasmic reticulum. In an immunological context, this event is followed by the binding of peptides to MHC molecules before export to the cell surface and recognition by T cells. Because TAP transport precedes MHC binding, TAP preferences may make a significant contribution to epitope selection. To assess the impact of this...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15557175
DOI: 10.4049/jimmunol.173.11.6813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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