Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Detailed Analysis of the Murine TAP Transporter Substrate Specificity

10 Jun 2008

Abstract excerpt

BACKGROUND: The transporter associated with antigen processing (TAP) supplies cytosolic peptides into the endoplasmic reticulum for binding to major histocompatibility complex (MHC) class I molecules. Its specificity therefore influences the repertoire of peptides presented by MHC molecules. Compared to human TAP, murine TAP's binding specificity has not been characterized as well, even though murine systems are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Immune Response and Inflammation
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18545702
DOI: 10.1371/journal.pone.0002402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Detailed Analysis of the Murine TAP Transporter Substrate SpecificityPMID 18545702Read ↗

Substrate selection by transporters associated with antigen processing occurs during peptide binding to TAP.Semantic proximity Read ↗

Principles of peptide selection by the transporter associated with antigen processingSemantic proximity Read ↗

Structure and Dynamics of Antigenic Peptides in Complex with TAPSemantic proximity Read ↗

Identifying MHC class I epitopes by predicting the TAP transport efficiency of epitope precursors.Semantic proximity Read ↗

The Transporter Associated With Antigen Processing (TAP): Structural Integrity, Expression, Function, and Its Clinical RelevanceSemantic proximity Read ↗

Absence of functional relevance of human transporter associated with antigen processing polymorphism for peptide selection.Semantic proximity Read ↗

Selection and binding of peptides to human transporters associated with antigen processing and rat cim-a and -b.Semantic proximity Read ↗

The role of tapasin in MHC class 1 antigen presentationSemantic proximity Read ↗

Dependence of peptide binding by MHC class I molecules on their interaction with TAP.Semantic proximity Read ↗

The principles of peptide selection by the transporter associated with antigen processingSemantic proximity Read ↗

Transporter associated with antigen processing preselection of peptides binding to the MHC: a bioinformatic evaluation.Semantic proximity Read ↗

A point mutation in the human transporter associated with antigen processing (TAP2) alters the peptide transport specificity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.