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Article

The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against C-terminal trimming of peptides in the ER.

Immunity - 1 Feb 1996

Powis S J, Young L L, Joly E, Barker P J, Richardson L, Brandt R P, Melief C J, Howard J C, Butcher G W

Abstract excerpt

Functional polymorphism in the rat peptide transporter associated with antigen processing (TAP) changes the peptide pool available for binding and presentation by a class I MHC allele, RT1.Aa. The peptide binding motif for RT1.Aa, determined by stabilization with synthetic peptides, included a strong preference for arginine at the peptide C terminus. Analysis of natural peptides bound to RT1.Aa by both pool...

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Identifiers

PMID: 8624806
DOI: 10.1016/s1074-7613(00)80680-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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