Article
Detection of the mutated K-Ras biomarker in colorectal carcinoma.
Experimental and molecular pathology - 1 Jun 2001
Doolittle B R, Emanuel J, Tuttle C, Costa J
Abstract excerpt
This study describes an advantageous, effective protocol for detecting K-Ras mutations in human stool as a prototype screen for colorectal carcinoma (CRC), the third most common malignancy in the United States. A reliable screening test that detects early lesions would contribute to a decrease in mortality. Currently, the only noninvasive screen for CRC is the hemeoccult, test which has a high false-positive...
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