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Article

Noninvasive detection through REMS-PCR technique of K-ras mutations in stool DNA of patients with colorectal cancer.

Journal of gastrointestinal and liver diseases : JGLD - 1 Mar 2007

Mixich Francisc, Ioana Mihai, Voinea Florea, Săftoiu Adrian, Ciurea Tudorel

Abstract excerpt

BACKGROUND AND AIMS: Tumor exfoliated cells that shed into stool are attractive targets for molecular screening and early detection of colon malignancies. Many studies have suggested that the detection of activated ras may have diagnostic or prognostic importance. The aim of this study was to establish the suitability for use in diagnostic laboratories of the noninvasive screening test of K-ras mutation...

Topics

Adolescent
Adult
Aged
Carcinoma
Colorectal Neoplasms
Feces
Female
Genes, ras
Humans
Male
Middle Aged
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Restriction Mapping

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Identifiers

PMID: 17410282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17410282-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Noninvasive detection through REMS-PCR technique of K-ras mutations in stool DNA of patients with colorectal cancer.PMID 17410282Read ↗

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