Article
Polygenic control of susceptibility to murine systemic lupus erythematosus.
Immunity - 1 Jun 1994
Morel L, Rudofsky U H, Longmate J A, Schiffenbauer J, Wakeland E K
Abstract excerpt
Susceptibility to glomerulonephritis (GN) and anti-dsDNA autoantibody production was analyzed in crosses with a newly developed systemic lupus erythematosus-susceptible inbred strain, NZM/Aeg2410. The mode of inheritance and the number and location of systemic lupus erythematosus-associated susceptibility loci were analyzed by interval mapping in a backcross with C57BL/6. Three chromosomal intervals containing...
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