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Article

Exclusion of close linkage of the dopamine transporter gene with schizophrenia spectrum disorders.

The American journal of psychiatry - 1 Jan 1995

Persico A M, Wang Z W, Black D W, Andreasen N C, Uhl G R, Crowe R R

Abstract excerpt

OBJECTIVE: Involvement of genetic factors in the pathogenesis of schizophrenia spectrum disorders has been indicated in twin, adoption, and familial aggregation studies; the pivotal role played by the dopamine transporter in dopaminergic neurotransmission makes it a candidate gene for these disorders. Detection of close linkage between a dopamine transporter marker and schizophrenia spectrum disorders would...

Topics

Alleles
Base Sequence
Carrier Proteins
Dopamine Plasma Membrane Transport Proteins
Genetic Linkage
Genetic Markers
Humans
Lod Score
Membrane Glycoproteins
Membrane Transport Proteins
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nerve Tissue Proteins

Pedigree

Phenotype

Schizophrenia

Source

Identifiers

PMID: 7802105
DOI: 10.1176/ajp.152.1.134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7802105-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Exclusion of close linkage of the dopamine transporter gene with schizophrenia spectrum disorders.PMID 7802105Read ↗

Absence of linkage between schizophrenia and the dopamine D4 receptor gene.Semantic proximity Read ↗

Genetic relationship between dopamine transporter gene and schizophrenia: linkage and association.Semantic proximity Read ↗

Linkage analysis of schizophrenia: the D1 dopamine receptor gene and several flanking DNA markers.Semantic proximity Read ↗

Alleles at the dopamine D4 receptor locus do not contribute to the genetic susceptibility to schizophrenia in a large Swedish kindred.Semantic proximity Read ↗

No evidence of linkage between the dopamine D2 receptor gene and schizophrenia.Semantic proximity Read ↗

Failure to find linkage between a functional polymorphism in the dopamine D4 receptor gene and schizophrenia.Semantic proximity Read ↗

Exclusion of linkage between schizophrenia and the gene encoding a neutral amino acid glutamate/aspartate transporter, SLC1A5.Semantic proximity Read ↗

Exclusion of linkage between schizophrenia and the D2 dopamine receptor gene region of chromosome 11q in 112 Irish multiplex families.Semantic proximity Read ↗

Analysis of the D4 dopamine receptor gene variant in an Italian schizophrenia kindred.Semantic proximity Read ↗

Linkage analysis between schizophrenia and a microsatellite polymorphism for the D5 dopamine receptor gene.Semantic proximity Read ↗

Lack of evidence for close linkage of the glutamate GluR6 receptor gene with schizophrenia.Semantic proximity Read ↗

No evidence for linkage between COMT and schizophrenia in a French population.Semantic proximity Read ↗

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