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Article

Exclusion of linkage between schizophrenia and the D2 dopamine receptor gene region of chromosome 11q in 112 Irish multiplex families.

Archives of general psychiatry - 1 Mar 1993

Su Y, Burke J, O'Neill F A, Murphy B, Nie L, Kipps B, Bray J, Shinkwin R, Ni Nuallain M, MacLean C J

Abstract excerpt

A leading theory hypothesizes that schizophrenia arises from dysregulation of the dopamine system in certain brain regions. As this dysregulation could arise from abnormal expression of D2 dopamine receptors, the D2 receptor gene (DRD2) on chromosome 11q is a candidate locus for schizophrenia. We tested whether allelic variation at DRD2 and five surrounding loci cosegregated with schizophrenia in 112 small- to...

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Source

Identifiers

PMID: 8439241
DOI: 10.1001/archpsyc.1993.01820150055005

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Exclusion of linkage between schizophrenia and the D2 dopamine receptor gene region of chromosome 11q in 112 Irish multiplex families.PMID 8439241Read ↗

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