Article
Lack of evidence for close linkage of the glutamate GluR6 receptor gene with schizophrenia.
The American journal of psychiatry - 1 Dec 1996
Chen A C, Kalsi G, Brynjolfsson J, Sigmundsson T, Curtis D, Butler R, Read T, Murphy P, Petursson H, Barnard E A, Gurling H M
Abstract excerpt
OBJECTIVE: Previous research has consistently implicated genetic factors in the pathogenesis of schizophrenia. It has been hypothesized that an abnormality in glutamatergic function is of etiologic importance in schizophrenia, and therefore the glutamate receptor family of genes are potential susceptibility loci for schizophrenia. To test this hypothesis the authors sought to detect linkage between the GluR6...
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