Article
Genetic relationship between dopamine transporter gene and schizophrenia: linkage and association.
Schizophrenia research - 1 May 1996
Maier W, Minges J, Eckstein N, Brodski C, Albus M, Lerer B, Hallmayer J, Fimmers R, Ackenheil M, Ebstein R E, Borrmann M, Lichtermann D, Wildenauer D B
Abstract excerpt
This study explores the genetic relationship between schizophrenia and the dopamine transporter gene (DAT) by a variety of methods. In a sample of 48 families--each family containing at least one nuclear family with a pair of affected siblings--we performed linkage analysis using the maximum like...
Topics
- Adult
- Carrier Proteins
- Chronic Disease
- Dopamine Plasma Membrane Transport Proteins
- Female
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Likelihood Functions
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Minisatellite Repeats
