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Article

No evidence for linkage between COMT and schizophrenia in a French population.

Psychiatry research - 10 May 2001

de Chaldée M, Corbex M, Campion D, Jay M, Samolyk D, Petit M, Thibaut F, Laurent C, Mallet J

Abstract excerpt

Catechol-O-methyltransferase is a candidate in the predisposition to schizophrenia both because of its function and the position of its gene. A multipoint non-parametric linkage analysis and a transmission disequilibrium test were performed on 42 multiplex families genotyped for Pml I and Bcl I polymorphisms using two definitions of the affected phenotype. Neither linkage nor preferential transmission of any...

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Source

Identifiers

PMID: 11368843
DOI: 10.1016/s0165-1781(01)00237-2

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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No evidence for linkage between COMT and schizophrenia in a French population.PMID 11368843Read ↗

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Linkage disequilibrium on the COMT gene in French schizophrenics and controls.Semantic proximity Read ↗

The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons.Semantic proximity Read ↗

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Lack of association of a functional catechol-O-methyltransferase gene polymorphism in schizophrenia.Semantic proximity Read ↗

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