No evidence for linkage between COMT and schizophrenia in a French population.

doi:10.1016/s0165-1781(01)00237-2

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Article

No evidence for linkage between COMT and schizophrenia in a French population.

Psychiatry research - 10 May 2001

de Chaldée M, Corbex M, Campion D, Jay M, Samolyk D, Petit M, Thibaut F, Laurent C, Mallet J

Abstract excerpt

Catechol-O-methyltransferase is a candidate in the predisposition to schizophrenia both because of its function and the position of its gene. A multipoint non-parametric linkage analysis and a transmission disequilibrium test were performed on 42 multiplex families genotyped for Pml I and Bcl I polymorphisms using two definitions of the affected phenotype. Neither linkage nor preferential transmission of any...

Topics

Alleles
Catechol O-Methyltransferase
Female
France
Gene Expression
Genetic Predisposition to Disease
Haplotypes
Humans
Linkage Disequilibrium
Male
Polymorphism, Genetic
Schizophrenia

Source

Open in PubMed

Identifiers

PMID: 11368843
DOI: 10.1016/s0165-1781(01)00237-2

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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