Article
Absence of linkage between schizophrenia and the dopamine D4 receptor gene.
Psychiatry research - 1 Jul 1994
Maier W, Schwab S, Hallmayer J, Ertl M A, Minges J, Ackenheil M, Lichtermann D, Wildenauer D
Abstract excerpt
The dopamine D4 receptor gene and the closely placed tyrosine hydroxylase (TH) receptor gene are important candidate genes for schizophrenia; both are located on the short arm of chromosome 11. Multipoint linkage analyses excluded linkage of schizophrenia/schizoaffective disorder to both candidate genes in a sample of 15 multiplex and systematically recruited families. This result was not dependent on the...
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