Article
Alleles at the dopamine D4 receptor locus do not contribute to the genetic susceptibility to schizophrenia in a large Swedish kindred.
American journal of medical genetics - 15 Dec 1993
Barr C L, Kennedy J L, Lichter J B, Van Tol H H, Wetterberg L, Livak K J, Kidd K K
Abstract excerpt
The discovery of a functional polymorphism within the dopamine D4 receptor gene (DRD4) has not only strengthened the hypotheses implicating DRD4 in the etiology of neuropyschiatric disorders, but also provided a genetic marker for testing these hypotheses. The possibility of the dopamine D4 receptor as a candidate gene for schizophrenia was investigated in a large Swedish kindred segregating for schizophrenia....
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