Article
Hoxa 11 structure, extensive antisense transcription, and function in male and female fertility.
Development (Cambridge, England) - 1 May 1995
Hsieh-Li H M, Witte D P, Weinstein M, Branford W, Li H, Small K, Potter S S
Abstract excerpt
Hoxa 11 is a murine Abdominal-B-type homeobox gene. The structure of this gene is presented, including genomic and cDNA sequence. The cDNA includes the complete open reading frame and based on primer extension results is near full length. Surprisingly, the antisense strand of Hoxa 11 was found to be transcribed. Moreover, these antisense transcripts were processed and polyadenylated. The developmental expression...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- DNA, Antisense
- Extremities
- Female
- Fertility
- Gene Expression
- Homeodomain Proteins
- In Situ Hybridization