Article
Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development.
Developmental biology - 15 May 2006
Schwab Kristopher, Hartman Heather A, Liang Hung-Chi, Aronow Bruce J, Patterson Larry T, Potter S Steven
Abstract excerpt
The Hox11 paralogous genes play critical roles in kidney development. They are expressed in the early metanephric mesenchyme and are required for the induction of ureteric bud formation and its subsequent branching morphogenesis. They are also required for the normal nephrogenesis response of the metanephric mesenchyme to inductive signals from the ureteric bud. In this report, we use microarrays to perform a...
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