Article
Hoxa-10 deficient male mice exhibit abnormal development of the accessory sex organs.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 1999
Podlasek C A, Seo R M, Clemens J Q, Ma L, Maas R L, Bushman W
Abstract excerpt
The role of mammalian Hox genes in regulating segmental patterning of axial structures and the limb is well established. A similar role in development of soft tissue organ systems has recently been suggested by observations linking several 5' members of the HoxA and HoxD clusters to segmentation...
Topics
- Animals
- DNA-Binding Proteins
- Gene Expression Regulation, Developmental
- Genitalia
- Genitalia, Male
- Homeobox A10 Proteins
- Homeodomain Proteins
- Male
- Mice
- Mutation
- Phenotype