Article
Generation and expression of a Hoxa11eGFP targeted allele in mice.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2008
Nelson Lisa T, Rakshit Sabita, Sun Hanshi, Wellik Deneen M
Abstract excerpt
Hox genes are crucial for body axis specification during embryonic development. Hoxa11 plays a role in anteroposterior patterning of the axial skeleton, development of the urogenital tract of both sexes, and proximodistal patterning of the limbs. Hoxa11 expression is also observed in the neural tube. Herein, we report the generation of a Hoxa11eGFP targeted knock-in allele in mice in which eGFP replaces the first...
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