Article
Hoxa-13 gene mutation results in abnormal seminal vesicle and prostate development.
The Journal of urology - 1 May 1999
Podlasek C A, Clemens J Q, Bushman W
Abstract excerpt
The role of Hoxa-13 in postnatal morphogenesis of the male accessory sex organs was assessed by correlating the Hoxa-13 expression domain with phenotypic abnormalities in heterozygous Hypodactyly mutants. Hypodactyly is a naturally occurring semi-dominant mutation that results from a 50-base pair deletion in exon one of the Hoxa-13 allele. We demonstrate that Hoxa-13 is broadly expressed in the developing lower...
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