Functional specificity of the Hoxa13 homeobox.

Abstract excerpt

To better define Abd-B type homeodomain function, to test models that predict functional equivalence of all Hox genes and to initiate a search for the downstream targets of Hoxa13, we have performed a homeobox swap by replacing the homeobox of the Hoxa11 gene with that of the Hoxa13 gene. The Hoxa11 and Hoxa13 genes are contiguous Abd-B type genes located at the 5' end of the HoxA cluster. The modified Hoxa11...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to In Situ Hybridization
• Share to Mice, Mutant Strains
• Share to Uterus