Article
Homeotic transformations and limb defects in Hox A11 mutant mice.
Genes & development - 1 Dec 1993
Small K M, Potter S S
Abstract excerpt
Hox A11 is one of the expanded set of vertebrate homeo box (Hox) genes with similarities to the Drosophila homeotic gene, Abdominal-B (Abd-B). These Abd-B-type Hox genes have been shown to be expressed in the most caudal regions of the developing vertebrate embryo and in overlapping domains within the developing limbs, suggesting that these genes play important roles in pattern formation in both appendicular and...
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