Article
High prevalence of p53 protein overexpression in patients with esophageal cancer in Linxian, China and its relationship to progression and prognosis.
Cancer - 15 Dec 1994
Wang D Y, Xiang Y Y, Tanaka M, Li X R, Li J L, Shen Q, Sugimura H, Kino I
Abstract excerpt
BACKGROUND: Linxian is the highest endemic area of esophageal squamous cell carcinoma (ESCC) in China and one of the highest incidence areas in the world. The relationship of p53 protein accumulation to geographic variation, pathologic findings, and prognosis has not been investigated extensively...
Topics
- Adult
- Carcinoma, Squamous Cell
- China
- Esophageal Neoplasms
- Female
- Follow-Up Studies
- Genes, p53
- Humans
- Immunohistochemistry
- Life Tables
- Male
- Middle Aged
- Mutation
- Neoplasm Invasiveness
- Prognosis
- Survival Rate
- Tumor Suppressor Protein p53