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Article

Frequent inactivation of the TP53 gene in esophageal squamous cell carcinoma from a high-risk population in China.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2001

Hu N, Huang J, Emmert-Buck M R, Tang Z Z, Roth M J, Wang C, Dawsey S M, Li G, Li W J, Wang Q H, Han X Y, Ding T, Giffen C, Goldstein A M, Taylor P R

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is one of the most common fatal cancers worldwide, and north central China has some of the highest rates in the world. Previous studies from tumors in this area of China have shown high frequencies of allelic loss on chromosome 17p13-11, which includes the region where the TP53 gene is found. We examined 56 ESCC patients using single-strand conformation polymorphism and...

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PMID: 11309337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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