Article
Environmental exposure and p53 mutations in esophageal cancer patients in areas of low and high incidence of esophageal cancer in China.
The Tohoku journal of experimental medicine - 1 Dec 2005
Sakaguchi Shigeko, Yokokawa Yoshiharu, Hou Jun, Zhang Xiu-Lan, Li Xiang-Ping, Li Shao-Sen, Li Xiao-Xian, Zhu De-Chen, Kamijima Michihiro, Yamanoshita Osamu, Nakajima Tamie
Abstract excerpt
Esophageal cancer is the 6th most common cancer in the world, and genetic factors (p53 mutations) in addition to the environmental factors (food, nutrition, smoking, drinking, etc.) are involved in its development. In this study, the association between the both factors, environmental risk factors for esophageal cancer and p53 mutations, in tumor tissues was investigated in 77 patients living in a high-incidence...
Topics
- Biopsy
- China
- Environmental Exposure
- Esophageal Neoplasms
- Family Health
- Feeding Behavior
- Female
- Genes, p53
- Humans
- Incidence
