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TP53 Mutations in Esophageal Squamous Cell Carcinoma.

Frontiers in bioscience (Landmark edition) - 24 Sept 2023

Zhong Leqi, Li Hongmu, Chang Wuguang, Ao Yong, Wen Zhesheng, Chen Youfang

Abstract excerpt

The occurrence and development of esophageal cancer involve multiple genetic abnormalities that contribute to the malignant transformation of esophageal epithelial cells, followed by invasion and metastasis, leading to a poor outcome. Esophageal squamous cell carcinoma (ESCC) is the predominant histological subtype of esophageal malignancy in East Asia, with approximately half of newly diagnosed ESCC cases...

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Identifiers

PMID: 37796679
DOI: 10.31083/j.fbl2809219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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