Article
Suggestions concerning the relationship between mutant frequency and mutation rate at the hprt locus in human peripheral T-lymphocytes.
Mutation research - 1 Jun 1995
Green M H, O'Neill J P, Cole J
Abstract excerpt
Mutant frequency is defined as the proportion of mutant cells in a population and is readily estimated. It should be distinguished from mutation rate, which relates to the rate at which mutation events arise, and is generally expressed as events per cell division. Since one mutation event may giv...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Cell Division
- Child
- Child, Preschool
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Infant
- Infant, Newborn
- Middle Aged
- Models, Genetic
- Mutagenesis
- Mutation
- Selection, Genetic
- T-Lymphocytes