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Article

In vivo hprt mutant frequencies in T-cells of normal human newborns.

Mutation research - 1 Feb 1990

McGinniss M J, Falta M T, Sullivan L M, Albertini R J

Abstract excerpt

Mutation at the hypoxanthine-guanine phosphoribosyl transferase locus (hprt; HPRT enzyme) in the human fetus was studied by clonal assay of placental cord blood samples from full-term newborns. Conditions for determining hprt mutant frequencies, as defined for adults, were also optimal for studie...

Topics

Adolescent
Adult
Antigens, CD
Antigens, Surface
Clone Cells
Female
Fetal Blood
Gene Frequency
Humans
Hypoxanthine Phosphoribosyltransferase
Infant, Newborn
Leukocytes, Mononuclear
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phenotype

T-Lymphocytes

Source

Identifiers

PMID: 2300072
DOI: 10.1016/0165-1218(90)90015-t

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2300072-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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In vivo hprt mutant frequencies in T-cells of normal human newborns.PMID 2300072Read ↗

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